An ambitious early career researcher is sought to join the Department of Biochemistry & Molecular Biology, Faculty of Medicine, Dentistry & Health Sciences in the University of Melbourne. The successful applicant will report to the laboratory head, Dr David Stroud. The Stroud lab seeks to apply systems biology approaches, incorporating extensive gene-editing and quantitative proteomics tools, as well as classical biochemical, molecular and cell biology techniques to understand the assembly of multi-subunit membrane protein complexes. More information on the lab can be found at http://www.bio21.unimelb.edu.au/stroud-group
The successful applicant will drive the computational proteomics & bioinformatics aspects of projects taking place in the lab. At the current time these include projects investigating the assembly of mitochondrial membrane protein complexes, the endosomal Commander complex, and development of complementary proteomics tools for diagnosis of mitochondrial disease. Practical experience in ThermoFisher Orbitrap LC-MS instrumentation and associated software (MaxQuant or Proteome Discoverer) is essential, along with experience performing related data analysis and bioinformatic workup. Familiar with associated wet lab procedures is essential and extensive experience, especially in mammalian cell culture, molecular and protein biochemistry will be highly advantageous.